GS-441524 is a compounded antiviral for treating feline infectious peritonitis (FIP), available through Wedgewood. Trusted by veterinarians and sourced from FDA-registered suppliers, it brings new confidence and consistency to FIP care.
Key Facts
Available in a Flavored Oral Oil Suspension: Customizable flavors for easy administration and compliance.
How It Works: Prior independent studies (linked below) have shown that it interferes with the FIP virus's enzymes or other biological processes.*
Dosage and Administration: Dosing varies from 10mg/kg to 20mg/kg once daily based on the cat's weight and the type of FIP – Effusive, Non-Effusive, Ocular, or Neurological. Current oral treatment recommendation entails daily dosing for 84 days (12 weeks).*
Side Effects: According to these independent studies, side effects are mild and infrequent.
Dating: The Beyond-Use Dating for Wedgewood’s GS-441524 is up to 90 days for the oral solution and may ship for office stock in most states.**
*We note that Wedgewood’s formulation containing GS-441524 has not been studied in any clinical trials. Wedgewood makes no claims of safety or efficacy with respect to the medications it produces and sells. The information provided herein is for informational purposes only.
**GS-441524 may only be shipped for office stock in states that allow office stock for 503A compounded preparations.
Independent Third-Party Studies
Some practitioners may find the studies which we provide below useful. The medications used in the studies were not provided by Wedgewood Pharmacy and we make no claim that the results found in the studies have any connection with or relevance to the results that may be achieved with any Wedgewood Pharmacy drug. The authors of this study are not endorsing in any manner any Wedgewood Pharmacy product and any implication to the contrary is expressly denied.
"Thirty-two cats with effusive or non-effusive feline infectious peritonitis treated with a combination of remdesivir and GS-441524"
by Green, et al.
“Retrospective study and outcome of 307 cats with feline infectious peritonitis treated with legally sourced veterinary compounded preparations of remdesivir and GS-441524 (2020-2022)”
by Taylor, et al.
"Feline Infectious Peritonitis: European Advisory Board on Cat Diseases Guidelines"
By Tasker, et al.
"Outcomes of treatment of cats with feline infectious peritonitis using parenterally administered remdesivir, with or without transition to orally administered GS-441524"
By Coggins, et al.
Dosing Calculator
The GS-441524 dosing protocol is based on independent clinical studies. This calculator is a tool that can be used to assist you in determining the dose needed for your unique case. Veterinarian professional and clinical judgement should ultimately determine the final dosing protocol.
"The recent availability of predictably effective antiviral treatments, notably the nucleoside analogue GS-441524, for FIP has totally changed the landscape of this disease for both owners and veterinary teams"
-Tasker, et al., "Feline Infectious Peritonitis: European Advisory Board on Cat Diseases Guidelines"
FAQs
What makes Wedgewood’s GS-441524 different from other suppliers?
Wedgewood offers GS-441524 sourced from FDA-registered suppliers with pharmacist support and consistent, high-quality compounding.
Can GS-441524 be used alongside Molnupiravir?
Yes, GS-441524 and Molnupiravir can be used together under veterinary supervision. They offer complementary antiviral mechanisms—GS-441524 blocks viral replication, while Molnupiravir induces lethal viral mutations. This combination or personalized use of one over the other can be adjusted based on patient response. Our pharmacists are available to help develop individualized treatment protocols, even in challenging cases.
Can my practice order GS-441524 for office stock?
GS-441524 can be shipped to hospitals for office stock in all states excep Colorado, Delaware, Hawaii, Louisiana, Maryland, Montana, New York, Oregon, Rhode Island, Connecticut, New Hampshire, New Mexico, South Dakota, and Washington D.C. Veterinarians who work in a state that does not allow compounded medications for office stock can prescribe GS-441524 in a patient’s name.
How long will it take for an order or prescription for GS-441524 to ship, and how long will it spend in transit?
Orders for GS-441524 are expected to ship within 1-2 business days. Time in transit will depend on the shipping method chosen.
Do you ship internationally?
We ship to all 50 states, Puerto Rico, the US Virgin Islands, Canada, Guam, and all US military bases worldwide.
What is the Beyond-Use Dating (BUD) for GS-441524?
The oral liquids will have a 90-day BUD from the date of compounding.
What quality control measures does Wedgewood follow?
We use FDA-registered APIs, rigorous compounding protocols, and maintain strict quality assurance.
Is there a risk of resistance with using GS-441524 or Molnupiravir?
While resistance can develop with any antiviral, using a combination approach or switching between GS-441524 and Molnupiravir under veterinary guidance can help mitigate this risk. Our pharmacists can support personalized strategies.
*We note that Wedgewood’s formulation containing GS-441524 has not been studied in any clinical trials. Wedgewood makes no claims of safety or efficacy with respect to the medications it produces and sells. The information provided herein is for informational purposes only.